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Keywords Chiral drugs;Asymmetric catalyse;Synthesis; 手性药物;不对称催化;合成;
Keywords chiral drug;enantiomer;racemate resolution; 手性药物;对映体;消旋体拆分;
Keywords chiral drugs;enantiomeric separation;HPLC;chiral stationary phases;stereoselective pharmacokinetics; 手性药物;对映体分离;高效液相色谱;手性固定相;立体选择性药物动力学;
Keywords Chiral ion-pair chromatography;Chiral ion-pair complex;Chiral drugs;Cinchona alkaloids;Camphorsulfonic acid; 手性离子对色谱法;手性离子对试剂;手性药物;金鸡纳生物碱;樟脑磺酸;
Keywords chiral drug;racemic switching;drug combination;chiral intermediates;chiral technology; 手性药物;外消旋转化;药物组合物;手性中间体;手性技术;
Chiral drugs are more important in new drugs. 手性药物在新药中越来越受重视。
Now, the most important thing is to obtain one of the chiral drug enantiomers. 因此,获得单一对映体的药物成为一项重要的工作。
The enantiomer of some chiral drugs has different pharmacology activity and different applying. 手性药物对映体具有不同的药理活性和不同的用途。
In this review the stereoselective pharmacodynamics of calciumchannel blockers and chiral drugs are summarized. 本文就以手性药物和钙通道阻滞剂的药效学立体选择性作一综述。
Resolution of racemic drugs by lipase catalysis offers an excellent technology for the preparation of single-isomer chiral drugs in organic solvent. 在有机相中,脂肪酶催化消旋体的拆分,为制备单异构体手性药物提供了重要的技术手段。
The resolution of some chiral drugs such as D,L-dansyl amino acid has certain rule, and provides information about absolute configuration. 对一些物质,如D,L-丹酰化氨基酸的拆分有一定的规律,能给出绝对构型信息。
Pharmacological interactions between the enantiomers may happen when a chiral drug was used as its racemate. 当手性药物以外消旋体供药用时,其对映体间就可能发生药效学和药代动力学的相互作用。
This article reviews the present applications of cyclodextrins in chiral drug resolution. 介绍了环糊精在手性药物拆分中的应用情况。
The selection of developing chiral drugs as strategy is on the important basis of chiral pharmacology study results but it is necessar... 选择手性药物开发战略的重要依据是手性药理学研究结果,同时还应综合考虑科学和经济学标准。
The selection of developing chiral drugs as strategy is on the important basis of chiral pharmacology study results but it is necessar. 基础生物化学研究推动手性药物市场持续增长,2001年单一对映体药物市场为1470亿美元,占世界药品市场4100亿美元的36%25。
Aim:To study the feasibility and influential factors for the resolution of HPLC-DAD data of chiral drugs by non-negative matrix factorization(NMF) algorithm. 目的:研究非负矩阵因子分解算法(NMF)用于手性药物HPLC-DAD二维数据解析的可行性及其影响因素。
The research progress on applications of MIP in chiral drug separation and clinical drug analysis in the recent years was expounded. 综述了近年来分子印迹聚合物在手性药物分离和临床药物分析应用方面的研究进展。
Keywords chiral diols;venlafaxine;systhesis; 手性邻二醇;文拉法辛;合成;
Keywords Chiral compounds;Enantiomorph;Separation; 手性化合物;对映体;拆分;
Keywords chiral;allylic amine;catalysis; 手性;烯丙基胺;催化;